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            當(dāng)前位置:首頁(yè)技術(shù)文章Vesicular Acetylcholine Transporter抗原,囊泡乙酰膽堿通道抗原

            Vesicular Acetylcholine Transporter抗原,囊泡乙酰膽堿通道抗原

            更新時(shí)間:2024-11-27點(diǎn)擊次數(shù):63

            Recombinant human Vesicular Acetylcholine Transporter   

            Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.     

            濃度:1mg/ ml

            來(lái)源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達(dá)系統(tǒng):Escherichia coli

            標(biāo)簽:His tag

            蛋白長(zhǎng)度:Full length protein

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質(zhì)期:1年

            Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
            VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.


            產(chǎn)品名稱(chēng):Rabbit Anti-Vesicular Acetylcholine Transporter  antibody

            Rabbit Anti-Vesicular Acetylcholine Transporter  

            別名:Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.    

            來(lái)源:Rabbit

            克隆類(lèi)型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):Human,Mouse,Rat (predicted: Rabbit)

            理論分子量:57kDa

            免疫原:KLH conjugated synthetic peptide derived from human Vesicular Acetylcholine Transporter

            保存:-20
            保質(zhì)期:1

             

            單克隆抗體

            產(chǎn)品名稱(chēng):Anti-Vesicular Acetylcholine Transporter antibody

            Mouse Anti-Vesicular Acetylcholine Transporter 

            別名:Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.   

            來(lái)源:Mouse

            克隆類(lèi)型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng): Human

            理論分子量:57kDa

            免疫原:KLH conjugated synthetic peptide derived from human Vesicular Acetylcholine Transporter

            保存:-20
            保質(zhì)期:1

            Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
            VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.


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