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            當(dāng)前位置:首頁(yè)技術(shù)文章VASP抗原,血管擴(kuò)張刺激磷蛋白抗原

            VASP抗原,血管擴(kuò)張刺激磷蛋白抗原

            更新時(shí)間:2024-12-11點(diǎn)擊次數(shù):55


            Recombinant human VASP   

            Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

            濃度:1mg/ ml

            來(lái)源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達(dá)系統(tǒng):Escherichia coli

            標(biāo)簽:His tag  

            蛋白長(zhǎng)度:Full length protein

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質(zhì)期:1年

            Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.




            產(chǎn)品名稱:Rabbit Anti-VASP  antibody

            Rabbit Anti-VASP  

            別名:Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

            來(lái)源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):Human,Mouse,Rat (predicted: Cow,Dog)

            理論分子量:40kDa

            免疫原:KLH conjugated synthetic peptide derived from human VASP

            保存:-20
            保質(zhì)期:1

             

            單克隆抗體

            產(chǎn)品名稱:Anti-VASP antibody

            Mouse Anti-VASP 

            別名:Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

            來(lái)源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng): Human

            理論分子量:40kDa

            免疫原:KLH conjugated synthetic peptide derived from human VASP

            保存:-20
            保質(zhì)期:1

            Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

             

             


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