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            當前位置:首頁資料下載VANGL2抗原,神經(jīng)管畸形相關蛋白VANGL2抗原

            VANGL2抗原,神經(jīng)管畸形相關蛋白VANGL2抗原

            發(fā)布時間:2024/12/11點擊次數(shù):31

            Recombinant human VANGL2  

            Homolog of Drosophila strabismus; KIAA1215; Loop tail associated protein; loop tail protein 1 homolog; Loop-tail protein 1 homolog; LPP 1; LPP1; LTAP; STB 1; STB1; STBM 1; STBM; STBM1; Strabismus 1; van Gogh like protein 2; Van Gogh-like protein 2; Vang (van gogh, Drosophila) like 2; Vang like 2 (van gogh, Drosophila); vang like 2; vang like protein 2; Vang-like protein 2; VANG2_HUMAN; VANGL 2; Vangl2.  

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達系統(tǒng):Escherichia coli

            標簽:His tag  

            蛋白長度:Full length protein

            內毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質期:1年

            The Vang family of proteins are integral membrane proteins that are homologs of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus1 (STB1), localizes on chromosome 1q22-q23. Vangl1 is expressed in testis and ovary, but also in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both down-regulated in several cancer cell lines and primary tumors.
            Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.




            產(chǎn)品名稱:Rabbit Anti-VANGL2  antibody

            Rabbit Anti-VANGL2

            別名:Homolog of Drosophila strabismus; KIAA1215; Loop tail associated protein; loop tail protein 1 homolog; Loop-tail protein 1 homolog; LPP 1; LPP1; LTAP; STB 1; STB1; STBM 1; STBM; STBM1; Strabismus 1; van Gogh like protein 2; Van Gogh-like protein 2; Vang (van gogh, Drosophila) like 2; Vang like 2 (van gogh, Drosophila); vang like 2; vang like protein 2; Vang-like protein 2; VANG2_HUMAN; VANGL 2; Vangl2.  

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應:Human (predicted: Mouse,Rat,Sheep,Cow)

            理論分子量:60kDa

            免疫原:KLH conjugated synthetic peptide derived from human VANGL2

            保存:-20
            保質期:1

            單克隆抗體

            產(chǎn)品名稱:Anti-VANGL2 antibody

            Mouse Anti-VANGL2

            別名:Homolog of Drosophila strabismus; KIAA1215; Loop tail associated protein; loop tail protein 1 homolog; Loop-tail protein 1 homolog; LPP 1; LPP1; LTAP; STB 1; STB1; STBM 1; STBM; STBM1; Strabismus 1; van Gogh like protein 2; Van Gogh-like protein 2; Vang (van gogh, Drosophila) like 2; Vang like 2 (van gogh, Drosophila); vang like 2; vang like protein 2; Vang-like protein 2; VANG2_HUMAN; VANGL 2; Vangl2.  

            源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應: Human

            理論分子量:60kDa

            免疫原:KLH conjugated synthetic peptide derived from human VANGL2

            保存:-20
            保質期:1

            The Vang family of proteins are integral membrane proteins that are homologs of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus1 (STB1), localizes on chromosome 1q22-q23. Vangl1 is expressed in testis and ovary, but also in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both down-regulated in several cancer cell lines and primary tumors.
            Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.



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