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            當(dāng)前位置:首頁資料下載Utrophin抗原,肌營養(yǎng)不良蛋白相關(guān)蛋白1抗原

            Utrophin抗原,肌營養(yǎng)不良蛋白相關(guān)蛋白1抗原

            發(fā)布時(shí)間:2024/12/18點(diǎn)擊次數(shù):24

            Recombinant human Utrophin   

            DHTX; Disrupted in heterotaxy; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance associated gene protein; UV radiation resistance-associated gene protein; UtrophinUtrophin_HUMAN.    

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達(dá)系統(tǒng):Wheat germ

            標(biāo)簽:GST tag N-Terminus

            蛋白長度:Protein fragment

            內(nèi)毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應(yīng)用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質(zhì)期:1年

            Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.


            抗體

            產(chǎn)品名稱:Rabbit Anti-Utrophin antibody

            Rabbit Anti-Utrophin  

            別名:DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin     

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng):Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog)

            理論分子量:394kDa

            免疫原:KLH conjugated synthetic peptide derived from Human Utrophin 

            保存:-20
            保質(zhì)期:1

             

            單克隆抗體

            產(chǎn)品名稱:Anti-Utrophin antibody

            Mouse Anti-Utrophin 

            別名:DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin  

            來源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應(yīng): Human 

            理論分子量:394kDa

            免疫原:KLH conjugated synthetic peptide derived from Human Utrophin  

            保存:-20
            保質(zhì)期:1

            Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.

             

             


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